Automated Sample Preparation and Analysis for Next-Generation Sequencing by Sandia National Labs To Be Presented at Knowledge Foundations Sample Prep 2013 Conference

Boston, MA (PRWEB) March 21, 2013

Industry leaders from around the world will convene in San Diego, CA for the Knowledge Foundations 7th Sample Prep 2013 conference which will take place at the San Diego Hilton & Resort on May 9 10. One of the many anticipated presentations will include Numrin Thaitrong, PhD, of Sandia National Labs as they present No-Spin Sample Preparation for Cartridge-Format Point-of-Care HIV Viral Load Testing

Presentation Abstract:

Automated Sample Preparation and Analysis for Next-Generation Sequencing

Numrin Thaitrong, PhD, of Sandia National Labs

Thorough characterization of next-generation sequencing library is a required process in the sample preparation workflow. However, this built-in quality control feature is currently not available for small-scale library construction platforms. We have developed an integrated droplet-based digital microfluidics (DMF) architecture with capillary interface to handle sub-microliter sample processing and analysis. The platform providing size distribution and quantization of the library can be coupled to the existing modular DMF hub to automate start-to-finish library construction. This presentation will be given by Numrin Thaitrong, PhD, of Sandia National Labs at Sample Prep 2013.

Sample Prep 2013 Program topics will include:

Robust methodologies for sample collection, (pre-)concentration, lysis, and target extraction
Critical role of sample prep in early diagnostics
Rapid sample-to-sequence techniques
Point-of-care sampling, detection and analysis
Sample preparation with micro- and nano fluidics
Robust sampling methodologies (automation, high-throughput, combinatorial approach in sample prep)
Alternative amplification techniques for sensitive sample prep
End-user prospective for biodetection and sampling technologies and devices
Alternative and disruptive approaches to sample preparation and applications
Field-ready devices: compatibility/reliability/scalability
Target enrichment and background depletion techniques
Isolation of dilute objects on cell and molecular levels
Immiscible phase purification
Novel methods of extraction from tough (non-filterable) matrices
Nucleic acid and protein based sample prep for next generation sequencing
Nanotechnology and miniaturization challenges for sample preparation
Standardization and regulatory issues in sample preparation across different applications

Distinguished Speaker Faculty:

-Charles Young, PhD, The Johns Hopkins University

-Richard Allen, PhD, Luminex Corporation

-John C. Carrano, PhD, Paratus Diagnostics, LLC

-Forest L. Rohwer, PhD, San Diego State University

-Sarah Fakih, PhD, QIAGEN GmbH, Germany

-Season Wong, PhD, AI Biosciences, Inc.

-Michael J. Heller, PhD, University of California San Diego

-Martin McDonnell, PhD, Defense Science and Technology Laboratory – DSTL Porton Down, United Kingdom

-Alexis Sauer-Budge, PhD, Fraunhofer USA

-Gregory Auner, PhD, Wayne State University

-Hafsa Korri-Youssoufi, PhD, University Paris-Sud, France

-Shan Gao, PhD, Wave 80 Biosciences, Inc.

-David Wright, Wi Medical Device Development, Inc.

-Mark W. Eshoo. PhD, Ibis Biosciences Inc., an Abbott Company

-Mark Tondra, PhD, Diagnostic Biosensors

-Patrick Broyer, PhD, bioM

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